São Paulo, Brazil’s economic centre, has solidified its position as the leading hub of the country’s health industry. The state boasts an advanced infrastructure, skilled labor force and a concentration of bioscience and pharmaceutical companies. São Paulo has successfully graduated from a regional leader to an emerging global player in health and medical research. São Paulo accounts for 38% of Brazil’s bioscience companies and 71% of its pharmaceutical industry, housing more than half of the nation’s workforce in this sector. The state’s healthcare ecosystem is extensive, with 22,000 public and private health establishments, including hospitals, clinics, and research centers. The health industry in São Paulo providing 22% of all hospital beds in Brazil. Out of the 109,000 hospital beds available in the state, 59% are funded by the public sector, reflecting São Paulo’s investments in accessible healthcare. The region and city boast a higher concentration of medical professionals than the national average as there are 2.73 physicians and 1.84 dentists per 1,000 inhabitants, which is significantly higher than the country’s overall figures. São Paulo is home to some of Brazil’s most prestigious medical institutions, which are at the forefront of research and specialized treatment. The Instituto do Coração (InCor) sets the benchmark for the treatment of heart disease. InCor’s multidisciplinary teams are involved in continuous knowledge exchange with global counterparts, ensuring that the institute remains at the cutting edge of cardiovascular medicine. São Paulo’s healthcare institutions are closely tied to the state's leading universities, creating a symbiotic relationship between education and practical healthcare delivery. Institutions like the São Paulo Hospital at the Federal University of São Paulo (Unifesp) and the Hospital das Clínicas at the University of São Paulo (USP) are integral to training the next generation of healthcare professionals while also advancing medical research and treatment.